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Life Extension, Optimized Folate (L-Methylfolate), 1000 mcg, 100 Veggie Caps

£30.50
Product code: FOLA-100-LIF

Availability: In Stock

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Quick Overview

Folate is involved in neurotransmitter synthesis and critical enzymatic reactions throughout the body. By depleting excess homocysteine, folate benefits cardiovascular health and nervous system function.

Those who take ordinary folate supplements, however, may not be experiencing its full spectrum of effects. This is because once ingested, not everyone converts folate to its biologically active form called 5-methyltetrahydrofolate (5-MTHF).Research shows that in a large proportion of the population, genetic enzyme deficiencies prevent the conversion of folate to 5-MTHF, leaving many vulnerable to low blood folate levels (and higher than desired homocysteine).

A more useful approach is to take the bioactive folate 5-MTHF directly, which has been declassified as a drug and is now available as a dietary supplement. 5-MTHF has been shown to dramatically raise red blood cell folate concentration, an indicator of folate status compared with folic acid supplementation. This bioactive folate is up to seven times more bioavailable than folic acid. This greater bioavailability is especially important in people who have a genetic enzyme deficiency since it requires no conversion to become metabolically active.

A study of 10 patients with endothelial dysfunction showed complete reversal of endothelial impairment after 5-MTHF supplementation compared with healthy control patients.

People with elevated homocysteine levels have a greater risk of cognitive decline. Unlike folic acid, 5-MTHF is able to cross the blood-brain barrier, which is especially important for people with cognitive difficulties to enhance the synthesis of acetylcholine in the brain — the neurotransmitter associated with memory.

Studies also show that the effectiveness of 5-MTHF can be further enhanced by co-supplementing with methylcobalamin (the active form of vitamin B12), vitamin B6, and riboflavin.
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Description Life Extension, Optimized Folate (L-Methylfolate), 1000 mcg, 100 Veggie Caps

Serving Size: 1 VegetarianTabletAmount Per Serving% Daily Value

SupplementFacts

\xa0
Folate as (6S)-5-Methyltetrahydrofolic acid,glucosamine salt1,000 mcg250%
Other Ingredients

Microcrystalline cellulose, dicalcium phosphate, croscarmellose sodium, silica, vegetable stearate, stearic acid.



Description
  • For Longer Life
  • Metabolically Active Form of Folic Acid
  • Dietary Supplement

Optimized Folate (L-Methylfolate)

Folate is involved in neurotransmitter synthesis and critical enzymatic reactions throughout the body. By depleting excess homocysteine, folate benefits cardiovascular health and nervous system function.

Those who take ordinary folate supplements, however, may not be experiencing its full spectrum of effects. This is because once ingested, not everyone converts folate to its biologically active form called  5-methyltetrahydrofolate (5-MTHF).Research shows that in a large proportion of the population, genetic enzyme deficiencies prevent the conversion of folate to 5-MTHF, leaving many vulnerable to low blood folate levels (and higher than desired homocysteine).

A more useful approach is to take the bioactive folate 5-MTHF directly, which has been declassified as a drug and is now available as a dietary supplement. 5-MTHF has been shown to dramatically raise red blood cell folate concentration, an indicator of folate status compared with folic acid supplementation. This bioactive folate is up to seven times more bioavailable than folic acid. This greater bioavailability is especially important in people who have a genetic enzyme deficiency since it requires no conversion to become metabolically active.

A study of 10 patients with endothelial dysfunction showed complete reversal of endothelial impairment after 5-MTHF supplementation compared with healthy control patients.

People with elevated homocysteine levels have a greater risk of cognitive decline. Unlike folic acid, 5-MTHF is able to cross the blood-brain barrier, which is especially important for people with cognitive difficulties to enhance the synthesis of acetylcholine in the brain — the neurotransmitter associated with memory.

Studies also show that the effectiveness of 5-MTHF can be further enhanced by co-supplementing with methylcobalamin (the active form of vitamin B12), vitamin B6, and riboflavin.

Suggested Use

Read the entire label and follow directions carefully prior to use.

Take one (1) capsule daily with food, or as recommended by a healthcare practitioner.

Other Ingredients

Microcrystalline cellulose, vegetable cellulose (capsule), silica, vegetable stearate.

This product contains no milk, egg, fish, peanuts, crustacean shellfish (lobster, crab, shrimp), soybeans, tree nuts, wheat, yeast, gluten, corn, or rice. Contains no sugar, and no artificial sweeteners, flavors, colors, or preservatives.

Warnings
  • Keep out of reach of children.
  • Do not exceed recommended dose.
  • Do not purchase if outer seal is broken or damaged.
  • When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

Store tightly closed in a cool, dry place.

Supplement Facts
Serving Size: 1 Vegetarian Capsule
 Amount per Serving% Daily Value
Folate [as (6S)-5-Methyltetrahydrofolic acid, glucosamine salt]1000 mcg250%


On the ingredients in this product the following EFSA-approved health claims are applicable

Folate - Folate contributes to maternal tissue growth during pregnancy
Folate - Folate contributes to normal amino acid synthesis
Folate - Folate contributes to normal blood formation
Folate - Folate contributes to normal homocysteine metabolism
Folate - Folate contributes to normal psychological function
Folate - Folate contributes to the normal function of the immune system
Folate - Folate contributes to the reduction of tiredness and fatigue
Folate - Folate has a role in the process of cell division

Recommended dosage

Read the entire label and follow the directions carefully prior to use. Take one (1) tablet daily with food, or as recommended by a healthcare practitioner. , Store tightly closed in a cool, dry place. Keep out of reach of children. Do not exceed recommended dose. Do not purchase if outer seal is broken or damaged. When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating. To report a serious adverse event or obtain product information, contact 1-866-280-2852.

Additional Information Life Extension, Optimized Folate (L-Methylfolate), 1000 mcg, 100 Veggie Caps



EAN Code737870193913
Manufacturer Part NumberLEX-14391
Original Product NameOptimized Folate 1000 mcg (100 Veggie Tabs) - Life Extension
Core Product NameOptimized Folate 1000 mcg
Product CategoryFolate
SKUFOLA-100-LIF
BrandLife Extension
Product TypeFood supplement
Weight (grams)100.0000
Package Quantity1
Package Size100
Type of unitsVeggie Tabs
Product Criteria100% Organic, 100% Vegetarian, Gluten Free, GMO Free
AllergiesNo
Does not containGluten, Wheat, Corn, Milk, Eggs, Soja, Nuts, Fish and shellfish, Artificial coloring, Artificial flavoring agents, Preservatives
Country of ManufactureUnited States
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