Why aren't your meds absorbing? If absorption seems inconsistent, you’re dealing with bioavailability problems. Bioavailability is the portion of a drug that becomes available in the body to have an effect. When this process isn’t working as expected, bioavailability problems can arise and influence how a medication performs. Several factors can drive bioavailability problems, including how a drug is formulated, how it travels through the body’s systems, and how it is processed by individual differences in metabolism. Other blockers include variability between people and the way a medication is released or dissolved in the body. Understanding these broad categories helps frame why some medications don’t absorb as anticipated. Simple, non-prescription approaches commonly discussed in clinical contexts focus on collaboration with a healthcare provider to review the medication’s formulation, explore alternatives, and ensure the plan aligns with the body’s processing patterns. This can involve considering different delivery options, checking for known interactions, and maintaining consistency in how a regimen is managed, all under the guidance of a professional. By recognizing bioavailability problems and staying engaged with your healthcare team, you can take an informed approach to how your meds are used. Use this information to prepare questions, track how a regimen behaves, and participate in decisions about how to manage your treatment plan. The emphasis is on understanding factors that influence absorption and using professional guidance to navigate options.