eggshell membrane side effects


eggshell membrane side effects


Eggshell Membrane Supplement: Benefits, Risks, and How to Choose (2026) - Topvitamine
Aug 03, 2026
What Is an Eggshell Membrane Supplement?An eggshell membrane supplement is a dietary product made from the thin, protein-rich layer inside eggshells. This membrane contains collagen, glucosamine, chondroitin sulfate, and hyaluronic acid, offering a multi-component approach to joint support in a single ingredient. Standardised forms such as NEM (Natural Eggshell Membrane) preserve the natural ratio of these compounds and have been used in most clinical research.Health Benefits and Scientific EvidenceStudies on eggshell membrane supplements show potential benefits for joint pain, flexibility, and skin health. A 2009 randomised controlled trial found that 500 mg of NEM daily reduced knee pain in people with osteoarthritis within eight weeks. More recent research has supported these findings. Biomarker studies also suggest eggshell membrane may slow cartilage breakdown, though longer-term studies are needed.Safety, Dosage, and How to ChooseThe most common dose is 500 mg per day, and benefits usually appear within 4 to 8 weeks. Eggshell membrane is generally well tolerated, but people with egg allergy should avoid it. Digestive side effects can occur. When choosing a product, look for NEM or another standardised form, verify third-party testing, and ensure at least 500 mg per serving.