Magnesium vs omega-3: which supplement wins for sleep, heart health, and inflammation? This page surveys the evidence landscape, differences in what each supplement is and how it is studied, and practical considerations for choosing between them. We focus on the science behind magnesium and omega-3, discuss typical dosage ranges, and offer tips to help you decide what might fit your needs. Note that individual responses vary and you should consult a healthcare professional before starting any new supplement plan. Science perspective: magnesium is a mineral involved in numerous bodily processes, whereas omega-3 refers to fatty acids such as EPA and DHA. The research base for sleep, cardiovascular markers, and inflammatory endpoints uses different study designs, populations, and outcome measures, so conclusions about magnesium vs omega-3 are not uniform. Some studies and analyses point to associations with certain endpoints, while others show limited or inconsistent effects. The quality of evidence can vary by formulation, dose, and duration, so interpretation requires attention to study details and real-world use. Dosage considerations: typical experimental ranges give magnesium around a few hundred milligrams of elemental magnesium per day, while omega-3 typically provides EPA+DHA in the low hundreds of milligrams per day, though higher doses are studied for specific indications. The choice of form matters—magnesium comes in several forms with different absorption and tolerability profiles, and omega-3 supplements differ in EPA vs DHA content and purity. Start with the lower end of the common ranges, monitor tolerance, and adjust as needed under professional guidance. Consider potential interactions with medications and existing supplements. Practical tips to choose between magnesium vs omega-3: assess your goals, preferred formulation, and budget; check product quality, third-party testing, and label transparency; plan a dosing schedule that fits your routine and minimizes GI upset or other tolerability issues; avoid multi-ingredient products if you want to isolate effects; and enlist clinician input if you have chronic conditions or take medications. The best choice often depends on individual factors, and many people use one or the other at different times or in combination under supervision. The key is to stay informed and tailor decisions to your circumstances.