perimenopause fatigue


perimenopause fatigue


menopause fatigue
Sep 14, 2026
Extreme fatigue during menopause is primarily caused by fluctuating and declining estrogen and progesterone, which disrupt sleep, mood-regulating neurotransmitters, and cellular energy production. Night sweats, sleep apnea, stress hormones, and midlife life demands compound the exhaustion. Because fatigue can also signal thyroid disorders, anemia, or depression, persistent exhaustion deserves a medical evaluation—and effective treatments, from lifestyle changes to hormone therapy, are available.