Plant-based nootropics are compounds derived from plants that researchers study for their potential cognitive effects. This page highlights science-backed picks, practical tips, and evidence-based guidance, with a focus on plant-based nootropics. The landscape varies by compound and study design, and much of the evidence comes from small human trials or laboratory work rather than large, definitive trials. Examples of plant-based nootropics commonly discussed in research include Bacopa monnieri, Ginkgo biloba, Rhodiola rosea, L-theanine, and Panax ginseng. For each, the evidence base ranges from encouraging signals to inconclusive results, depending on the outcome measured and the quality of the study. We summarize what systematic reviews and meta-analyses say about these compounds, noting that findings are often task-specific and not universally consistent across populations. Practical tips for evaluating plant-based nootropics include checking for standardized extracts and clearly labeled active constituents, looking for independent testing, preferring products with transparent sourcing, and being aware of potential interactions with medications. Consider the origin of the extract and the formulation, how the study designs compare to real-world use, and how long trials typically lasted. If you have medical considerations, consulting a healthcare professional before incorporating any new option is prudent. Evidence-based guidance and critical thinking involve interpreting research with attention to the type of evidence (in vitro, animal, human), sample size, blinding, and duration. Be mindful of publication bias and conflicts of interest, and rely on credible sources such as peer-reviewed reviews and clinical trials. As the science of plant-based nootropics evolves, staying informed about the quality of evidence and updates in guidelines can help support informed decisions.