Prebiotic supplements are products designed to deliver non-digestible substrates that may influence the gut microbial environment. This page centers on science-backed prebiotic supplements, outlining what they are, the kinds of ingredients they contain, and how researchers think about their role within the broader gut ecosystem. Common ingredients in prebiotic supplements include inulin, fructooligosaccharides (FOS), galactooligosaccharides (GOS), and resistant starches. These compounds are typically not broken down in the small intestine and thus become available to microbes in the colon. Research on prebiotic supplements tends to focus on microbial metabolism, substrate availability, and the composition and activity of gut communities under different conditions. Quality and evidence matter when evaluating prebiotic supplements. Look for transparent ingredient labeling, dosage information, and whether a product has undergone third-party testing or certification. Consider the source of the ingredients, the manufacturing standards of the facility, and any allergen statements. A careful review of the evidence base for specific ingredients can help inform your choices within the category of prebiotic supplements. Getting started with prebiotic supplements involves consideration of personal goals and tolerability. If you are considering a product, review the label, begin with a conservative amount if recommended, and seek guidance from a qualified professional if you have questions about suitability. This page aims to help you understand the landscape of prebiotic supplements and how to identify science-backed options.