progesterone and anxiety
progesterone and anxiety
Progesterone plays a key role in mood regulation by converting to allopregnanolone, which enhances GABA activity. For many women, especially during perimenopause, progesterone can significantly reduce anxiety. However, the response varies based on individual factors, including PMDD and GABA receptor sensitivity. This guide explains the mechanisms, when progesterone helps, and when it may cause issues, with practical advice on dosing and natural support.