Understanding the supplement efficacy period helps readers grasp how long a product is expected to stay within its labeled potency under typical storage. This window depends on formulation, packaging, and handling, and it can shift with environmental conditions. Because potency can decline after manufacturing, the supplement efficacy period is an estimate rather than a guarantee, and it will differ from product to product. Several factors affect potency during the supplement efficacy period. Exposure to light, heat, and moisture accelerates degradation, while air exposure and oxidation can change the composition over time. Packaging design—such as amber glass bottles, blister packs, or vacuum sealing—plays a protective role, and the specific product matrix (powders, capsules, or soft gels) also influences stability. The age of the product and how it has been stored prior to purchase add to variability in the supplement efficacy period. Practical storage tips to support the supplement efficacy period include storing in a cool, dry place away from direct sunlight and heat sources. Keep containers tightly closed when not in use and retain them in their original packaging whenever possible. If a desiccant is included, leave it in the container; avoid transferring products to humid environments like bathrooms. For items that specify refrigeration, follow those directions; otherwise, most products are intended for room-temperature storage. Check the label for the expiration date and any notes about the supplement efficacy period. Because the period is an estimate, real-world conditions can shorten or extend it. When in doubt about storage age, replacing older stock can help maintain alignment with your product inventory. For product-specific guidance, refer to the manufacturer’s instructions.