Discover evidence-based supplement prescription guidelines that support safe, consistent practice across care settings. These guidelines provide an evidence-informed framework for considering supplementation, with emphasis on dosing, interactions, risk assessment, and personalized strategies to guide decision-making. By standardizing approaches, supplement prescription guidelines help clinicians apply best practices while accommodating individual patient contexts. The emphasis is on transparent processes, quality sources, and ongoing evaluation as evidence evolves. Within supplement prescription guidelines, dosing is approached with a principle of cautious initiation, appropriate formulation consideration, and clear titration plans. Clinicians assess factors such as formulation bioavailability, patient age and organ function, and timing relative to other therapies to determine an initial dose and sequence of adjustments. Documentation of the chosen dose, planned adjustments, and monitoring parameters is required to support safe management. Ongoing review ensures dosing remains appropriate as circumstances change. Interaction screening is a core element of supplement prescription guidelines. Practitioners evaluate potential interactions with prescription medications, over-the-counter products, and other supplements, and they assess contraindications based on patient history and current conditions. A structured risk assessment includes allergy status, comorbidities, pregnancy or lactation considerations, and product quality and contamination risk. Safeguards such as selecting reputable products, verifying labeling, and planning monitoring align with professional standards. Personalized strategies within supplement prescription guidelines emphasize shared decision-making, patient preferences, and realistic goals. Care plans are tailored to the individual's health priorities, lifestyle, and risk tolerance, with clear follow-up and criteria for adjusting or stopping treatment. As new evidence emerges, plans are updated, and deprescribing criteria are defined to maintain appropriate use.